产品货号：
Z18902
中文名称：
IKBKB抗体
英文名称：
Anti-IKBKB Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-IKBKB Antibody |
| 指标别名 | I kappa B kinase 2;I kappa B kinase beta;IKBKB;IKK B;IKK beta;IKK2;IKKB;IκB;NFKBIKB |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | IHC,WB |
| 基因名称 | IKBKB |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | IKKb peptide corresponding to the highly conserved C-terminus region of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH). |
| 成分 | 0.01% (w/v) Sodium Azide |
| 纯化方式 | This product was prepared from monospecific antiserum by delipidation and defibrination.Anti-IKKb may react non-specifically with other proteins.?Control peptide (code #100-401-220p) will compete only with the specific reaction of antiserum with the IKKb subunit. |
| 浓度 | 80mg/mL by Refractometry |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | NFkB comprises a family of cellular transcription factors that are involved in the inducible expression of a variety of cellular genes that regulate the inflammatory response and control of cell death.In the cytoplasm NFkB is negatively modulated by the inhibitory proteins IkB.In turn IkB is phosphorylated by a cellular kinase complex called IKK.IKK is a heterodimer composed of two kinases:IKK-a and IKK-b that phosphorylate IkB leading to its degradation and the resulting translocation of NFkB to the nucleus.IKK kinase activity is modulated negatively by pharmaceutical agents such as aspirin and positively by various cellular components such as TNF- a,endotoxins and overexpression of cellular kinases like MEKK1.Aspirin appears to have its effect by inhibiting the binding of ATP to IKK. |
| Uniprot ID | O14920 |
| 推荐稀释比 | ELISA:1:1,000 - 1:5,000 IHC:1:200 - 1:1,000 WB:1:200 - 1:1,000 |
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